About 1 result found for searched term "KDOAM-25 trihydrochloride " (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M31018 | KDOAM-25 trihydrochloride | Histone demethylase |
| KDOAM-25 trihydrochloride is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells. | ||
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